{"id":76714,"date":"2023-05-22T06:02:16","date_gmt":"2023-05-22T13:02:16","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-renal-fibroblasts\/"},"modified":"2026-07-08T14:51:43","modified_gmt":"2026-07-08T21:51:43","slug":"human-renal-fibroblasts","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-renal-fibroblasts\/","title":{"rendered":"Human Renal Fibroblasts"},"content":{"rendered":"

Product Description<\/strong><\/span><\/span><\/p>\n

Fibroblasts and myofibroblasts are believed to be the key effector cells in renal fibrogenesis responsible for the synthesis and deposition of extracellular matrix components [1]<\/sup>. Although fibroblasts are histologically visible in normal kidneys, there are relatively few of them and proximal tubular epithelial cells predominate. In progressive disease, however, the interstitium becomes filled with myofibroblasts [2]<\/sup>. Fibroblasts are considered the primary matrix-producing cells in the kidney and hence they are clinically relevant as principal mediators of renal fibrosis associated with progressive renal failure [3]<\/sup>.<\/p>\n

iXCells Biotechnologies<\/strong> provides high quality Human Renal Fibroblasts, which are isolated from adult human kidney tissue and cryopreserved at P1, with >0.5 million cells in each vial. Human Renal Fibroblasts express fibronectin and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand no more than 3 passages in Fibroblast Growth Medium (Cat# MD-0011<\/a>) under the condition suggested by iXCells Biotechnologies.<\/p>\n

 <\/p>\n

\"Human<\/p>\n

Figure 1. Human Renal Fibroblasts<\/strong>. (A) Phase contrast image. (B) Immunofluorescence staining with antibodies against Vimentin.<\/p>\n

 <\/p>\n

Product Details<\/strong><\/span><\/span><\/p>\n\n\n\n\n\n\n\n\n\n
Tissue<\/strong><\/td>\nNormal human kidney tissue<\/td>\n<\/tr>\n
Package Size<\/strong><\/td>\n0.5 million cells\/vial<\/td>\n<\/tr>\n
Passage Number<\/strong><\/td>\nP1<\/td>\n<\/tr>\n
Shipped<\/strong><\/td>\nCryopreserved<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nLiquid nitrogen<\/td>\n<\/tr>\n
Growth Properties<\/strong><\/td>\nAdherent<\/td>\n<\/tr>\n
Media<\/strong><\/td>\nFibroblast Growth Medium (Cat# MD-0011)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Reference<\/strong><\/span><\/span><\/p>\n

[1] Soma Meran and Robert Steadman (2011) \u201cFibroblasts and myofibroblasts in renal fibrosis\u201d. Int. J. Exp. Path. 92: 158\u2013167<\/p>\n

[2] H. Terence Cook. (2010) \u201cThe Origin of Renal Fibroblasts and Progression of Kidney Disease\u201d. The American Journal of Pathology, 176 (1):22-24.<\/p>\n

[3] Frank Strutz and Michael Zeisberg. (2002) \u201cRenal Fibroblasts and Myofibroblasts in Chronic Kidney Disease\u201d. JASN, 17: 2992-2998.<\/p>\n

 <\/p>\n

Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Product Description Fibroblasts and myofibroblasts are believed to be the key effector cells in renal fibrogenesis responsible for the synthesis and deposition of extracellular matrix components [1]. Although fibroblasts are histologically visible in normal kidneys, there are relatively few of them and proximal tubular epithelial cells predominate. 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