{"id":74355,"date":"2023-05-22T05:44:43","date_gmt":"2023-05-22T12:44:43","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/mouse-bone-marrow-derived-macrophage-mbmdm\/"},"modified":"2026-08-11T13:08:17","modified_gmt":"2026-08-11T20:08:17","slug":"mouse-bone-marrow-derived-macrophage-mbmdm","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/mouse-bone-marrow-derived-macrophage-mbmdm\/","title":{"rendered":"Mouse Bone Marrow Derived Macrophage (mBMDM)"},"content":{"rendered":"

Product Description<\/strong><\/span><\/span><\/p>\n

Macrophages are a type of white blood cell differentiated from circulating bone marrow-derived monocytes. Macrophages are responsible for detecting, engulfing and digesting cellular debris, apoptotic cells, and invading pathogens in a process called phagocytosis. Macrophages can be identified by several specific cell surface proteins including CD11b, CD14, F4\/80 (mice)\/EMR1 (human), MAC-1\/MAC-3, and CD68 by immunohistochemistry or flow cytometry analysis [1]<\/sup>. T Bone marrow-derived macrophages are suitable for numerous applications including phagocytosis, gene expression profiling, and Morphological examination of cytospins using histological stains (e.g., May-Gr\u00fcnwald-Giemsa staining), etc.[2]<\/sup>.<\/p>\n

iXCells Biotechnologies <\/strong>provides Mouse Bone Marrow Derived Macrophage (mBMDM), which were differentiated in the presence of M-CSF using the bone marrow cells isolated from adult C57BL\/6 mice (Figure 1). mBMDM are harvested at P0 and delivered freshly or frozen. For frozen cells, each vial contains \u2265 5 million cells in 1 mL volume. mBMDMs are characterized by flow cytometry analysis with >97% CD11b+ purity (Figure 2). mBMDMs are negative for mycoplasma, bacteria, yeast, and fungi. It is recommended to use Macrophage Culture Medium (Cat # MD-0097) for in vitro<\/em> culturing of mBMDM. However, mBMDMs are not recommended for long-term cultures or further expansion.<\/p>\n

\"Mouse-Bone-Marrow-Derived-Macrophage-data-ixcells<\/a><\/p>\n

Figure 1.<\/strong> Mouse Bone Marrow Derived Macrophage (mBMDM). (A) Phase contrast images. (B) The purity of the mBMDM was measured using CD11b+ antibody by flow cytometry analysis.<\/p>\n

Product Details<\/strong><\/p>\n\n\n\n\n\n\n\n\n
Tissue<\/strong><\/td>\nMouse Bone Marrow<\/td>\n<\/tr>\n
Package Size<\/strong><\/td>\n5 million cells\/vial<\/td>\n<\/tr>\n
Shipped<\/strong><\/td>\nCryopreserved<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nLiquid nitrogen<\/td>\n<\/tr>\n
Growth Properties<\/strong><\/td>\nAdherent<\/td>\n<\/tr>\n
Media<\/strong><\/td>\nMacrophage Culture Medium (Cat# MD-0097)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

References<\/span><\/strong><\/span><\/p>\n

[1]. Cline MJ and Sumner MA. Bone Marrow Macrophage Precursors. I. Some Functional Characteristics of the Early Cells of the Mouse Macrophage Series. Blood. 1972; 40: 62-69.<\/p>\n

[2]. Wynn TA and Barron L. Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis. 2010; 30: 245-57.<\/p>\n

Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Product Description Macrophages are a type of white blood cell differentiated from circulating bone marrow-derived monocytes. Macrophages are responsible for detecting, engulfing and digesting cellular debris, apoptotic cells, and invading pathogens in a process called phagocytosis. Macrophages can be identified by several specific cell surface proteins including CD11b, CD14, F4\/80 (mice)\/EMR1 (human), MAC-1\/MAC-3, and CD68 […]<\/p>\n","protected":false},"featured_media":108576,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1632],"product_tag":[],"cell_type":[2419],"cell_system":[2425],"organ":[2449],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-74355","product","type-product","status-publish","has-post-thumbnail","product_cat-animal-primary-cells","cell_type-immune-cells","cell_system-immune-and-hematopoietic-system","organ-blood-peripheral-blood-immune-system","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"\nMouse Bone Marrow Derived Macrophage (mBMDM) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/mouse-bone-marrow-derived-macrophage-mbmdm\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mouse Bone Marrow Derived Macrophage (mBMDM) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Macrophages are a type of white blood cell differentiated from circulating bone marrow-derived monocytes. 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