{"id":74336,"date":"2023-05-22T05:44:40","date_gmt":"2023-05-22T12:44:40","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neurons-rcn\/"},"modified":"2026-07-14T14:13:31","modified_gmt":"2026-07-14T21:13:31","slug":"rat-cortical-neurons-rcn","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neurons-rcn\/","title":{"rendered":"Rat Cortical Neurons (RCN)"},"content":{"rendered":"<p><span style=\"font-size: 16px\"><span style=\"color: #ff7300\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p style=\"text-align: justify\">Cortical neurons make up a large portion of the brain and consist of both glutamateric and GABA-ergic neurons <sup>[1]<\/sup>. They play an important role in higher level thought processes and are necessary to organize input from subcortical structures. Like all neurons, these cells transport Na+ that work to propagate action potentials from one cell to the next, which is the basis of a working neural pathway. These cells can be used to study a variety of cortical related abnormalities including Huntington\u2019s Disease, Alzheimer\u2019s Disease, psychiatric disorders, and learning disorders <sup>[2, 3]<\/sup>.<\/p>\n<p style=\"text-align: justify\">iXCells Biotechnologies provides high quality Rat Cortical Neurons (RCN), which are isolated from the brains of E16 embryonic rats. These cells are cryopreserved at P0, with \u2265 2 million cells in each vial. They are negative for mycoplasma, bacteria, yeast, and fungi. RCNs can be plated using Rat Cortical Neuron Recovery Medium (<a href=\"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neuron-recovery-medium\/\" target=\"_blank\" rel=\"noopener\">Cat# MD-0107A<\/a>) and maintained in Rat Cortical Neuron Maintenance Medium (<a href=\"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neuron-maintenance-medium\/\" target=\"_blank\" rel=\"noopener\">Cat# MD-0107B<\/a>) under the condition suggested by iXCells Biotechnologies.<\/p>\n<p><img decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/07\/Rat_Cortical_Neurons.webp\" alt=\"Rat Cortical Neurons\" \/><\/p>\n<p style=\"text-align: center\"><strong>Figure 1. <\/strong>Rat Cortical Neuron (Cat# 10RA-032) were recovered and cultured for 5 days. (A) Phase contrast image. (B) Immunofluorescence staining were performed using antibodies against the neuronal markers MAP2 (green) and NeuN (red).<\/p>\n<p><strong style=\"font-size: 16px;line-height: 22.4px;color: #ff7300\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.7999992370605px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px;vertical-align: middle\"><span style=\"line-height: 20.8px\">Tissue<\/span><\/td>\n<td style=\"width: 592px;vertical-align: middle\"><span style=\"line-height: 20.8px\"> D16 embryo r<\/span><span style=\"line-height: 20.8px\">at brain tissue<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 135px\"><span style=\"line-height: 20.8px\">Package Size<\/span><\/td>\n<td style=\"width: 592px;vertical-align: middle\"><span style=\"line-height: 20.8px\"> 2.0 millioncells\/vial <\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><span style=\"line-height: 20.8px\">Passage Number<\/span><\/td>\n<td style=\"width: 592px\"><span style=\"line-height: 20.8px\"> P0<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><span style=\"line-height: 20.8px\">Shipped<\/span><\/td>\n<td style=\"width: 592px\"><span style=\"line-height: 20.8px\"> Cryopreserved<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><span style=\"line-height: 20.8px\">Storage<\/span><\/td>\n<td style=\"width: 592px\"><span style=\"line-height: 20.8px\"> Liquid nitrogen<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><span style=\"line-height: 20.8px\">Growth Properties<\/span><\/td>\n<td style=\"width: 592px\"><span style=\"line-height: 20.8px\"> Adherent<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><span style=\"line-height: 20.8px\">Media<\/span><\/td>\n<td style=\"width: 592px\">Rat Cortical Neuron Recovery Medium (<a href=\"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neuron-recovery-medium\/\" target=\"_blank\" rel=\"noopener\">Cat# MD-0107A<\/a>)<br \/>\nRat Cortical Neuron Maintenance Medium (<a href=\"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neuron-maintenance-medium\/\" target=\"_blank\" rel=\"noopener\">Cat# MD-0107B<\/a>)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b style=\"color: #ff7300\">Reference<\/b><\/p>\n<p>[1] Johnson M, Walsh C. (2017) &#8221; Cerebral Cortical Neuron Diversity and Development at Single-Cell Resolution &#8221; Curr Opin Neurobiol. 42: 9-16.<\/p>\n<p>[2] Lim L, Mi D, Llorca A, Marin O. (2018) &#8221; Development and functional diversification of cortical interneurons.&#8221; Neuron. 100(2): 294-313.<\/p>\n<p>[3] Moln\u00e1r Z, Clowry G J, \u0160estan N, Alzu\u2019bi A, Bakken T, Hevner R F, et al. (2019) &#8221; New insights into the development of the human cerebral cortex.&#8221; J. Anat. 235: 432-451.<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Rat_Cortical_Neuron_V2.pdf\" target=\"_blank\" rel=\"noopener\">Download Datasheet<\/a><\/p>\n<p><em>*Holiday discount is not applicable to this product *<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Cortical neurons make up a large portion of the brain and consist of both glutamateric and GABA-ergic neurons [1]. They play an important role in higher level thought processes and are necessary to organize input from subcortical structures. Like all neurons, these cells transport Na+ that work to propagate action potentials from one [&hellip;]<\/p>\n","protected":false},"featured_media":90453,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1632],"product_tag":[],"cell_type":[2420],"cell_system":[2426],"organ":[2439],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-74336","product","type-product","status-publish","has-post-thumbnail","product_cat-animal-primary-cells","cell_type-neurons-and-glial-cells","cell_system-nervous-system","organ-brain-central-nervous-system","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rat Cortical Neurons (RCN) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/rat-cortical-neurons-rcn\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rat Cortical Neurons (RCN) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Cortical neurons make up a large portion of the brain and consist of both glutamateric and GABA-ergic neurons [1]. 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