{"id":74314,"date":"2023-05-22T05:44:36","date_gmt":"2023-05-22T12:44:36","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-adscs-type-1-diabetes\/"},"modified":"2026-07-08T14:41:43","modified_gmt":"2026-07-08T21:41:43","slug":"human-adipose-derived-stem-cells-adscs-type-1-diabetes","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-adscs-type-1-diabetes\/","title":{"rendered":"Human Adipose Derived Stem Cells (ADSCs, Type 1 Diabetes)"},"content":{"rendered":"<p><span style=\"font-size: 16px\"><span style=\"color: #ff7300\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p>Human Adipose-Derived Stem cells (ADSCs) are isolated from human lipoaspirate tissue collected during elective surgical liposuction procedures. ADSCs are available for <a href=\"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-hadsc-normal\/\" target=\"_blank\" rel=\"noopener\">normal<\/a> donors, patients with Type 1 Diabetes, <a href=\"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-adscs-type-2-diabetes\/\" target=\"_blank\" rel=\"noopener\">Type 2 Diabetes<\/a>, or <a href=\"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-adscs-obesity\/\" target=\"_blank\" rel=\"noopener\">Obesity (BMI&gt;30)<\/a>. It has been shown that the ADSCs demonstrate very similar phenotypic and functional characteristics to that of bone marrow-derived mesenchymal stem cells. Thousands of articles have been published on ADSCs using a variety of terminology, including preadipocytes, adipose-derived mesenchymal stem cells (AD-MSCs), adipose MSCs (AMSCs), adipose-derived adult stem (ADAS) cells, and adipose stromal\/stem cells (ASCs). Normal human ADSCs have been reported to differentiate into many different lineages including chondrogenic, osteogenic, adipogenic and neural. And have been applied in studies include stem cell differentiation, regenerative medicine <sup>[1]<\/sup>, and cell therapy <sup>[2]<\/sup>.<\/p>\n<p><strong>iXCells Biotechnologies<\/strong> offers normal human adipose-derived stem cells (hADSC) from adipose tissues from single donor, and cryopreserved at passage 1. hADSC are positive for CD29, CD44, CD73, CD90, CD105, and negative for CD14, CD31, CD45 (<strong>Figure 1<\/strong>). hADSC can be in vitro differentiated into adipocytes and osteoblasts (<strong>Figure 2 and 3<\/strong>) using <a href=\"https:\/\/ixcellsbiotech.com\/product\/adipocyte-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Adipocyte Differentiation Medium (Cat# MD-0005)<\/a> and <a href=\"https:\/\/ixcellsbiotech.com\/product\/osteogenic-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Osteogenic Differentiation Medium (Cat# MD-0006)<\/a>, separately. hADSC can be further expanded for 3-4 passages using <a style=\"line-height: 20.8px\" href=\"https:\/\/ixcellsbiotech.com\/product\/adipose-derived-stem-cell-growth-medium\/\" target=\"_blank\" rel=\"noopener\">Adipose-Derived Stem CellGrowth Medium (Cat# MD-0003)<\/a>. These cells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.<\/p>\n<p>&nbsp;<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/ADSCs.jpg\" alt=\"Human ADSCs\" width=\"900\" height=\"268\" \/><\/p>\n<p style=\"text-align: center\"><strong>Figure 1. <\/strong>Immunostaining of cell surface markers of human ADSC.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><img decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human-ADSC-adipocyte-differentiation.jpg\" alt=\"Adipogenic Induction\" width=\"600\" height=\"221\" \/><\/p>\n<p style=\"text-align: center\"><strong>Figure 2.<\/strong>Human ADSC adipocyte differentiation (Day 14 post adipogenic induction).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><img decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/hADSC-osteogenic-induction.jpg\" alt=\"Osteogenic induction\" width=\"600\" height=\"373\" \/><\/p>\n<p align=\"center\"><strong>Figure 3.<\/strong>Human ADSC osteogenic induction (Day 24 post osteogenic induction). Alizarin Red S staining of osteoblasts. The extracellular calcium deposit was stained in bright orange-red color.<\/p>\n<p>&nbsp;<\/p>\n<p><strong style=\"font-size: 16px;line-height: 22.3999996185303px;color: #ff7300\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">Human adipose tissue from liposuction procedures<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong> Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5 million cells\/vial;1.0 million cells\/vial (available for Normal)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong> Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong> Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong> Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 135px\"><strong> Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong> Media<\/strong><\/td>\n<td style=\"width: 592px\"><a href=\"https:\/\/ixcellsbiotech.com\/product\/adipose-derived-stem-cell-growth-medium\/\" target=\"_blank\" rel=\"noopener\">Adipose-Derived Stem Cell Growth Medium (Cat# MD-0003)<\/a><br \/>\n<a href=\"https:\/\/ixcellsbiotech.com\/product\/adipocyte-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Adipocyte Differentiation Medium (Cat# MD-0005)<\/a><br \/>\n<a href=\"https:\/\/ixcellsbiotech.com\/product\/osteogenic-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Osteogenic Differentiation Medium (Cat# MD-0006)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><strong><span style=\"color: #ff7300\">References<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px\">[1] Harasymiak-Krzyzanowska I et al. Adipose tissue-derived stem cells show considerable promise for regenerative medicine applications. Cell Mol Biol Lett. 2013; 18(4): 479-493.<\/span><\/p>\n<p><span style=\"font-size: 14px\">[2] Bertheuil N, et al and Tarte K. Adipose-derived stromal cells: history, isolation, immunomodulatory properties and clinical perspective. Ann Chir Plast Esthet. 2015;60(2): 94-102.<\/span><\/p>\n<p style=\"line-height: 20.7999992370605px\"><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human_Adipose_Derived_Stem_Cells_hADSC_V2.pdf\" target=\"_blank\" rel=\"noopener\">Download Datasheet<\/a><\/p>\n<div>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Adipocyte_Differentiation_Protocol_V2.pdf\" target=\"_blank\" rel=\"noopener\">Adipocyte Differentiation Protocol<\/a><\/p>\n<div><\/div>\n<div><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Osteogenic_Differentiation_Protocol_V2.pdf\" target=\"_blank\" rel=\"noopener\">OsteogenicDifferentiation Protocol<\/a><\/div>\n<\/div>\n<div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Human Adipose-Derived Stem cells (ADSCs) are isolated from human lipoaspirate tissue collected during elective surgical liposuction procedures. ADSCs are available for normal donors, patients with Type 1 Diabetes, Type 2 Diabetes, or Obesity (BMI&gt;30). It has been shown that the ADSCs demonstrate very similar phenotypic and functional characteristics to that of bone marrow-derived [&hellip;]<\/p>\n","protected":false},"featured_media":108577,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1835,1644],"product_tag":[],"cell_type":[2418],"cell_system":[1721],"organ":[2448],"disease":[2455],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-74314","product","type-product","status-publish","has-post-thumbnail","product_cat-diseases-modeling","product_cat-human-primary-cells","cell_type-stem-cells","cell_system-adipose-stromal-system","organ-adipose-tissue","disease-type-1-diabetes","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Adipose Derived Stem Cells (ADSCs, Type 1 Diabetes) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-adipose-derived-stem-cells-adscs-type-1-diabetes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Adipose Derived Stem Cells (ADSCs, Type 1 Diabetes) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Human Adipose-Derived Stem cells (ADSCs) are isolated from human lipoaspirate tissue collected during elective surgical liposuction procedures. 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