{"id":74113,"date":"2023-05-22T05:42:57","date_gmt":"2023-05-22T12:42:57","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/mouse-meningeal-cells-mmc\/"},"modified":"2023-07-28T06:13:07","modified_gmt":"2023-07-28T13:13:07","slug":"mouse-meningeal-cells-mmc","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/mouse-meningeal-cells-mmc\/","title":{"rendered":"Mouse Meningeal Cells (MMC)"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-size: 14pt;\"><strong>*** Product available by custom isolation only, please contact us to <a href=\"https:\/\/5176862.extforms.netsuite.com\/app\/site\/crm\/externalleadpage.nl\/compid.5176862\/.f?formid=8&amp;h=AAFdikaIHLKEukB9P_KfjbDOtxOZxhR8sm3tff5M3xp4lunfeUM&amp;redirect_count=1&amp;did_javascript_redirect=T\" target=\"_blank\" rel=\"noopener\">get a quote<\/a>. ***<\/strong><\/span><\/p>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><span style=\"color: #ff8c00;\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p>Meningeal cells surrounding the brain participate actively in the normal development of the central nervous system. For example, they play important roles in both stabilizing the extracellular matrix of the pial surface and by organizing the radial glial scaffold and the lamination of the cerebellar cortex [1]. Selective pharmacological destruction of the meningeal cells during a critical ontogenetic period leads to specific malformation of both the cerebella cortex and dentate gyrus [1]. Grafts of meningeal cells, which are derived from meninges overlying the cerebral cortex in adult rat spinal cord lesion, promote axonal regrowth [2]. In vitro study show that meningeal cell chemotactically orients the migration of immature neurons but not glial cells [3].<\/p>\n<p>iXCells Biotechnologies provides high quality Mouse Meningeal Cells (MMC), which are isolated from mouse leptomeningi and cryopreserved at P1, with &gt;0.5 million cells in each vial. MMC express fibronectin and are negative to GFAP, alpha-smooth muscle actin and Thy 1. MMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 5 population doublings in <a href=\"https:\/\/ixcellsbiotech.com\/product\/meningeal-cell-growth-medium\/\">Meningeal Cell Growth Medium (Cat# MD-0050)<\/a> under the condition suggested by iXCells Biotechnologies.<\/p>\n<p style=\"line-height: 20.7999992370605px;\"><strong style=\"color: #ff8c00; font-size: 14px; line-height: 22.3999996185303px;\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.7999992370605px; width: 724px;\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px;\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px;\">M<span style=\"line-height: 18.9091px;\">ouse leptomeningi (strain C57BL\/6 or CD1) <\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px;\">0.5 million cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px;\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px;\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px;\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px;\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px;\"><a style=\"line-height: 18.9091px;\" href=\"https:\/\/ixcellsbiotech.com\/product\/meningeal-cell-growth-medium\/\">Meningeal Cell Growth Medium (Cat# MD-0050)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><strong><span style=\"color: #ff8c00;\">References<\/span><\/strong><\/span><\/p>\n<p>[1] Hartmann, D., Sievers, J. Pehlemann, F. W. and Berry, M. (1992) Destruction of meningeal cells over the medial cerebral hemisphere of newborn hamster prevents the formation of the infrapyramidal blade of the dentate gyrus. J. Comparative Neurol. 320:33-61.<\/p>\n<p>[2] Franzen, R., Martin, D., Daloze, A., Moonen, G. and Schoenen, J. (1999) Grafts of meningeal fibroblasts in adult rat spinal cord lesion promote axonal regrowth. Neuroreport 10:1551-1556.<\/p>\n<p>[3] Hartmann, D., Schulze, M. and Sievers, J. (1998) Meningeal cells stimulate and direct the migration of cerebellar external granule cells in vitro. J. Neurocytol. 27:395-409.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Meningeal cells surrounding the brain participate actively in the normal development of the central nervous system. For example, they play important roles in both stabilizing the extracellular matrix of the pial surface and by organizing the radial glial [&hellip;]<\/p>\n","protected":false},"featured_media":108603,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1632],"product_tag":[],"cell_type":[],"cell_system":[],"organ":[],"disease":[],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-74113","product","type-product","status-publish","has-post-thumbnail","product_cat-animal-primary-cells","first","instock","taxable","shipping-taxable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mouse Meningeal Cells (MMC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/mouse-meningeal-cells-mmc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mouse Meningeal Cells (MMC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Meningeal cells surrounding the brain participate actively in the normal development of the central nervous system. 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