{"id":74107,"date":"2023-05-22T05:42:55","date_gmt":"2023-05-22T12:42:55","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/mouse-brain-vascular-pericytes-mbvp\/"},"modified":"2026-07-10T11:08:42","modified_gmt":"2026-07-10T18:08:42","slug":"mouse-brain-vascular-pericytes-mbvp","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/mouse-brain-vascular-pericytes-mbvp\/","title":{"rendered":"Mouse Brain Vascular Pericytes (MBVP)"},"content":{"rendered":"

Product Description<\/strong><\/span><\/span><\/p>\n

Brain Vascular Pericytes (BVP) are perivascular cells that are closely associated with the endothelium of capillaries and other small vessels [1]<\/sup>. BVP, located between endothelial cells and astrocytes in the brain, communicate with other cells by extending long cytoplasmic processes which wrap around the capillaries [1, 2]<\/sup>. BVP participate in a variety of processes including angiogenesis, endothelial cell survival, regulation of capillary blood flow, and establishment and maintenance of the blood-brain barrier [3,4]<\/sup>. Pericyte dysregulation has been linked to several pathological conditions such as hypertension, diabetic retinopathy, atherosclerosis, multiple sclerosis, Alzheimer\u2019s disease, and tumor angiogenesis [2, 4]<\/sup>. The unique and diverse functions of BVP make them novel candidates for cell therapy in regenerative medicine. Cultured primary mouse BVP (MBVP) are a useful in vitro model for understanding the molecular mechanisms of blood-brain barrier regulation and for studying a wide variety of central nervous system diseases.<\/p>\n

iXCells Biotechnologies<\/strong> provides high quality Mouse Brain Vascular Pericytes (MBVP), which are isolated from adult mouse brain and cryopreserved at P2, with >0.5 million cells in each vial. MBVP express Neural\/glial antigen 2 (NG2) and \u03b1-smooth muscle actin. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand no more than 3 passages in Mouse Pericyte Growth Medium (Cat# MD-0030<\/a>) under the condition suggested by iXCells Biotechnologies. Additional expansion may decrease the purity and proliferation rate.<\/p>\n

\"Mouse<\/p>\n

Figure 1. <\/strong>Mouse Brain Vascular Pericytes (MBVP). (A<\/strong>) Phase contrast image of MBVP. (B<\/strong>) Immunofluorescence staining with antibody against NG2.<\/p>\n

Product Details<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n
Tissue<\/strong><\/td>\nAdult mouse brain<\/span><\/td>\n<\/tr>\n
Package Size<\/strong><\/td>\n0.5 millioncells\/vial<\/td>\n<\/tr>\n
Passage Number<\/strong><\/td>\nP2<\/td>\n<\/tr>\n
Shipped<\/strong><\/td>\nCryopreserved<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nLiquid nitrogen<\/td>\n<\/tr>\n
Growth Properties<\/strong><\/td>\nAdherent<\/td>\n<\/tr>\n
Media<\/strong><\/td>\nPericyte Growth Medium (Cat# MD-0030)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

References<\/span><\/strong><\/span><\/p>\n

[1] Dore-Duffy P, Cleary K. (2011) “Morphology and properties of pericytes.” Methods Mol Biol. 686:49-68.<\/p>\n

[2] Allt G, Lawrenson JG. (2001) “Pericytes: cell biology and pathology.” Cells Tissues Organs. 169: 1-11.<\/p>\n

[3] Daneman R, Zhou L, Kebede A, Barres B. (2010) “Pericytes are required for blood-brain barrier integrity during embryogenesis.” Nature. 468:562-566.<\/p>\n

[4] Kutcher M, Herman I. (2009) “The pericyte: cellular regulator of microvascular blood flow.” Microvasc Res. 77: 235-246.<\/p>\n

Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Product Description Brain Vascular Pericytes (BVP) are perivascular cells that are closely associated with the endothelium of capillaries and other small vessels [1]. BVP, located between endothelial cells and astrocytes in the brain, communicate with other cells by extending long cytoplasmic processes which wrap around the capillaries [1, 2]. BVP participate in a variety of […]<\/p>\n","protected":false},"featured_media":108585,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1632],"product_tag":[],"cell_type":[2420],"cell_system":[2426],"organ":[2439],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-74107","product","type-product","status-publish","has-post-thumbnail","product_cat-animal-primary-cells","cell_type-neurons-and-glial-cells","cell_system-nervous-system","organ-brain-central-nervous-system","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"\nMouse Brain Vascular Pericytes (MBVP) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/mouse-brain-vascular-pericytes-mbvp\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mouse Brain Vascular Pericytes (MBVP) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Brain Vascular Pericytes (BVP) are perivascular cells that are closely associated with the endothelium of capillaries and other small vessels [1]. 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