{"id":73996,"date":"2023-05-22T05:39:21","date_gmt":"2023-05-22T12:39:21","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-skeletal-muscle-satellite-cells-hskmsc\/"},"modified":"2023-08-04T00:38:32","modified_gmt":"2023-08-04T07:38:32","slug":"human-skeletal-muscle-satellite-cells-hskmsc","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-skeletal-muscle-satellite-cells-hskmsc\/","title":{"rendered":"Human Skeletal Muscle Satellite Cells (HSkMSC)"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-size: 14pt;\"><strong>*** Product available by custom isolation only, please contact us to <a href=\"https:\/\/5176862.extforms.netsuite.com\/app\/site\/crm\/externalleadpage.nl\/compid.5176862\/.f?formid=8&amp;h=AAFdikaIHLKEukB9P_KfjbDOtxOZxhR8sm3tff5M3xp4lunfeUM&amp;redirect_count=1&amp;did_javascript_redirect=T\" target=\"_blank\" rel=\"noopener\">get a quote<\/a>. ***<\/strong><\/span><\/p>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><span style=\"color: #ff8c00;\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p>Skeletal muscle contains both differentiated myofibers and stem cells, known as satellite cells. The satellite cells, comprising around 1% of the total muscle nuclei, are situated between the plasma membrane of the multinucleated muscle cells and the basal lamina that surrounds each myofiber. In adult muscle, satellite cells are quiescent but proliferate in response to muscle injury, producing myoblasts that can either form new satellite cells or fuse with one another or pre-existing multinucleated muscle cells to help repair the muscle. They are responsible for postnatal muscle growth, hypertrophy and regeneration of skeletal muscle [1]. When quiescent satellite cells are activated, they co-express the transcription factors Pax7 and myoD [2].<\/p>\n<p>iXCells Biotechnologies provides high quality Human Skeletal Muscle Satellite Cells (HSkMSC), which are isolated from human muscle of the pectoral girdle and cryopreserved at P1, with &gt;0.5 million cells in each vial. HSkMSC express myosin, actin and actinin. These HSkMSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 12 population doublings in <a style=\"line-height: 18.9091px;\" href=\"https:\/\/ixcellsbiotech.com\/product\/skeletal-muscle-cell-growth-medium\/\">Skeletal Muscle Cell Growth Medium (Cat# MD-0052)<\/a> under the condition suggested by iXCells Biotechnologies.<\/p>\n<p><strong style=\"color: #ff8c00; font-size: 14px; line-height: 22.4px;\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px; width: 724px;\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px;\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px;\">H<span style=\"line-height: 20.8px;\">uman <\/span><span style=\"line-height: 18.9091px;\">muscle of the pectoral girdle<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Package Size<\/strong><\/td>\n<td style=\"width: 592px;\">0.5 million cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Passage Number<\/strong><\/td>\n<td style=\"width: 592px;\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Shipped<\/strong><\/td>\n<td style=\"width: 592px;\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Storage<\/strong><\/td>\n<td style=\"width: 592px;\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Growth Properties<\/strong><\/td>\n<td style=\"width: 592px;\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Media<\/strong><\/td>\n<td style=\"width: 592px;\"><a style=\"line-height: 18.9091px;\" href=\"https:\/\/ixcellsbiotech.com\/product\/skeletal-muscle-cell-growth-medium\/\">Skeletal Muscle Cell Growth Medium (Cat# MD-0052)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><strong><span style=\"color: #ff8c00;\">References<\/span><\/strong><\/span><\/p>\n<p>[1] Villena, J., Brandan, E. (2004) Dermatan sulfate exerts an enhanced growth factor response on skeletal muscle satellite cell proliferation and migration. J Cell Physiol. 198(2):169-78.<\/p>\n<p>[2] Morris, R. T., Spangenburg, E. E., Booth, F. W. (2004) Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle. J Appl Physiol. 96(1):398-404.<\/p>\n<p>[3] Al-Khalili, L., Chibalin, A. V., Kannisto, K., Zhang, B. B., Permert, J., Holman, G. D., Ehrenborg, E., Ding, V. D., Zierath, J. R., Krook, A. (2004) Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content. Cell Mol Life Sci. 60(5):991-8.<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human Skeletal Muscle Satellite Cells.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"line-height: 0;\" tabindex=\"-1\"><img decoding=\"async\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/pdf.jpg\" alt=\"\" width=\"30\" height=\"30\" data-widget=\"image\" \/><span style=\"left: 0px; background: url(;\"><img decoding=\"async\" title=\"Click and drag to move\" draggable=\"draggable\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/wAAACH5BAEKAAAALAAAAAABAAEAAAICRAEAOw%3D%3D\" alt=\"\" width=\"15\" height=\"15\" \/><\/span><\/span>Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Skeletal muscle contains both differentiated myofibers and stem cells, known as satellite cells. The satellite cells, comprising around 1% of the total muscle nuclei, are situated between the plasma membrane of the multinucleated muscle cells and the basal [&hellip;]<\/p>\n","protected":false},"featured_media":99726,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[],"cell_system":[],"organ":[],"disease":[],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73996","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","first","instock","taxable","shipping-taxable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Skeletal Muscle Satellite Cells (HSkMSC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-skeletal-muscle-satellite-cells-hskmsc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Skeletal Muscle Satellite Cells (HSkMSC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Skeletal muscle contains both differentiated myofibers and stem cells, known as satellite cells. 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