{"id":73988,"date":"2023-05-22T05:39:19","date_gmt":"2023-05-22T12:39:19","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-mesenchymal-stem-cells-humsc\/"},"modified":"2026-07-08T14:22:56","modified_gmt":"2026-07-08T21:22:56","slug":"human-umbilical-mesenchymal-stem-cells-humsc","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-mesenchymal-stem-cells-humsc\/","title":{"rendered":"Human Umbilical Mesenchymal Stem Cells (HUMSC)"},"content":{"rendered":"<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><span style=\"color: #ff7300\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p style=\"text-align: justify\">Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. MSC have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. These properties, in combination with their developmental plasticity, have generated tremendous interest because of the potential use of MSC in regenerative medicine. MSC isolated from the Wharton\u2019s jelly of the umbilical cord were induced to transform into neurons and glia in vitro by using neuron-conditioned medium, sonic hedgehog, and FGF-8 <sup>[1, 2]<\/sup>. MSC can also differentiate into cells from the adipogenic and osteogenic lineage. Additionally, they have the potential to differentiate into cardiomyocytes by culturing them in cardiomyocyte-conditioned medium <sup>[3]<\/sup>. MSC express the matrix receptors CD44 and CD105 and mesenchymal stem cell markers SH2 and SH3, but not the hematopoietic lineage marker CD34.<\/p>\n<p style=\"text-align: justify\">Human Umbilical Mesenchymal Stem Cells (HUMSC)from <strong>iXCells Biotechnologies <\/strong>are isolated from Wharton\u2019s jelly of the umbilical cord. HUMSC are cryopreserved at passage one and delivered frozen. Each vial contains 0.5 million cells in 1 ml volume. HUMSC are characterized by immunofluorescence with antibodies specific to CD73, CD90 and CD105. HUMSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HUMSC can expand for no more than 3 passages under the conditions recommended by iXCells Biotechnologies using\u00a0 <a href=\"https:\/\/ixcellsbiotech.com\/product\/mesenchymal-stem-cell-medium\/\" target=\"_blank\" rel=\"noopener\">Mesenchymal Stem Cell Medium (Cat# MD-0037)<\/a>.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human_Umbilical_Mesenchymal_Stem_Cells.png\" alt=\"Human Umbilical Mesenchymal Stem Cells\" width=\"1092\" height=\"285\" \/><\/p>\n<p style=\"text-align: center;font-size: 12px\"><strong>Figure 1.<\/strong> Human Umbilical Mesenchymal Stem Cells (HUMSC). (<strong>A<\/strong>) Phase contrast image of HUMSC. (<strong>B<\/strong>) Immunofluorescence staining with antibodies against CD29 and CD90.<\/p>\n<p><strong style=\"color: #ff7300;font-size: 16px;line-height: 22.4px\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 140px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">Human Umbilical Cord<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5 million cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px\"><a style=\"line-height: 18.9091px\" href=\"https:\/\/ixcellsbiotech.com\/product\/mesenchymal-stem-cell-medium\/\" target=\"_blank\" rel=\"noopener\">Mesenchymal Stem Cell Medium (Cat# MD-0037)<\/a><br \/>\n<a href=\"https:\/\/ixcellsbiotech.com\/product\/adipocyte-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Adipocyte Differentiation Medium (Cat# MD-0005)<\/a><br \/>\n<a href=\"https:\/\/ixcellsbiotech.com\/product\/osteogenic-differentiation-medium\/\" target=\"_blank\" rel=\"noopener\">Osteogenic Differentiation Medium (Cat# MD-0006)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><strong><span style=\"color: #ff7300\">References<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify\">[1] Mitchell, K. E. et al. (2003) Matrix cells from Wharton&#8217;s jelly form neurons and glia. Stem Cells 21:50-60.<\/p>\n<p style=\"text-align: justify\">[2] Fu, Y. S. et al. (2006) Conversion of human umbilical cord mesenchymal stem cells in Wharton&#8217;s jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonium. Stem cells 24:115-124.<\/p>\n<p style=\"text-align: justify\">[3] Wang, H. S., et al., (2004) Mesenchymal stem cells in the Wharton&#8217;s jelly of the human umbilical cord. Stem cells 22:1330-1337.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human_Umbilical_Mesenchymal_Stem_Cells_V2.pdf\" target=\"_blank\" rel=\"noopener\">Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. MSC have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. These properties, in combination with their developmental plasticity, have generated tremendous interest because of the potential use of MSC in regenerative medicine. MSC isolated [&hellip;]<\/p>\n","protected":false},"featured_media":90308,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2418],"cell_system":[2435],"organ":[2437],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73988","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-stem-cells","cell_system-general-stem-cell-and-ipsc-platform","organ-umbilical-cord-placenta","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Umbilical Mesenchymal Stem Cells (HUMSC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-mesenchymal-stem-cells-humsc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Umbilical Mesenchymal Stem Cells (HUMSC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. 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