{"id":73832,"date":"2023-05-22T05:37:42","date_gmt":"2023-05-22T12:37:42","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-mammary-epithelial-cells-hmepc\/"},"modified":"2026-06-18T15:11:03","modified_gmt":"2026-06-18T22:11:03","slug":"human-mammary-epithelial-cells-hmepc","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-mammary-epithelial-cells-hmepc\/","title":{"rendered":"Human Mammary Epithelial Cells (HMEpC)"},"content":{"rendered":"<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 14px\"><span style=\"color: #ff8c00\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p style=\"text-align: justify\">Human mammary epithelial cells (HMEpC) lie within the alveolar lumen of the breast lobules, which together with mammary ducts and adipose tissues, form a complex network in the mammary gland. HMEpC respond to various growth factors and hormonal cues and undergo changes in growth, invasion, and differentiation during pre- and postnatal stage, puberty, and pregnancy <sup>[1]<\/sup>. Aberrant levels of hormones and extracellular matrix composition, and other genetic factors have been shown to induce uncontrolled proliferation of HMEpC, resulting in breast cancer development <sup>[2, 3]<\/sup>. Therefore, understanding the cellular properties of HMEpC will help identify the disease mechanisms in breast cancer and the new targets for therapeutic development.<\/p>\n<p style=\"text-align: justify\">iXCells Biotechnologies offers high quality HMEpC, which are isolated from human breast and cryopreserved at P1, with &gt;0.5 million cells in each vial. HMEpC express cytokeratine-14, -18, and -19. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for no more than 3 passages in <a style=\"line-height: 18.9091px\" href=\"https:\/\/ixcellsbiotech.com\/product\/epithelial-cell-growth-medium\/\">Epithelial Cell Growth Medium (Cat# MD-0041)<\/a> under the conditions suggested by iXCells Biotechnologies.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/07\/10HU-104_Human_Mammary_Epithelial_Cells.webp\" alt=\"10HU 104 Human Mammary Epithelial Cells\" width=\"2227\" height=\"831\" \/><\/p>\n<p><strong>Figure 1:<\/strong> Phase contrast and cytokeratin 14 (C K 14) staining of HMEpC post recovery<\/p>\n<p>&nbsp;<\/p>\n<p><strong style=\"color: #ff8c00;font-size: 14px;line-height: 22.4px\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">H<span style=\"line-height: 20.8px\">uman <\/span><span style=\"line-height: 18.9091px\">breast<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5 million cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px\"><a style=\"line-height: 18.9091px\" href=\"https:\/\/ixcellsbiotech.com\/product\/epithelial-cell-growth-medium\/\">Epithelial Cell Growth Medium (Cat# MD-0041)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 14px\"><strong><span style=\"color: #ff8c00\">References<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify\">[1]. Topper, Y.J., Freeman, C.S. (1980) Multiple hormone interactions in the developmental biology of the mammary gland. Physiol Rev 60:1049-106.<\/p>\n<p style=\"text-align: justify\">[2]. Hennighausen, L., Robinson, G.W. (2001) Signaling pathways in mammary gland development. Dev Cell 1:467-475.<\/p>\n<p style=\"text-align: justify\"><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/10HU-104_Human_Mammary_Epithelial_Cells_V00.pdf\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/pdf.jpg\" alt=\"\" width=\"30\" height=\"30\" \/>Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Human mammary epithelial cells (HMEpC) lie within the alveolar lumen of the breast lobules, which together with mammary ducts and adipose tissues, form a complex network in the mammary gland. HMEpC respond to various growth factors and hormonal cues and undergo changes in growth, invasion, and differentiation during pre- and postnatal stage, puberty, [&hellip;]<\/p>\n","protected":false},"featured_media":90265,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2416],"cell_system":[2432],"organ":[2451],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73832","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-epithelial-cells","cell_system-reproductive-and-placental-system","organ-reproductive-organs","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Mammary Epithelial Cells (HMEpC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-mammary-epithelial-cells-hmepc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Mammary Epithelial Cells (HMEpC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Human mammary epithelial cells (HMEpC) lie within the alveolar lumen of the breast lobules, which together with mammary ducts and adipose tissues, form a complex network in the mammary gland. 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