{"id":73774,"date":"2023-05-22T05:37:31","date_gmt":"2023-05-22T12:37:31","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-prostate-microvascular-endothelial-cells-hpmec\/"},"modified":"2023-08-06T22:14:25","modified_gmt":"2023-08-07T05:14:25","slug":"human-prostate-microvascular-endothelial-cells-hpmec","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-prostate-microvascular-endothelial-cells-hpmec\/","title":{"rendered":"Human Prostate Microvascular Endothelial Cells (HPMEC)"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-size: 14pt;\"><strong>*** Product available by custom isolation only, please contact us to <a href=\"https:\/\/5176862.extforms.netsuite.com\/app\/site\/crm\/externalleadpage.nl\/compid.5176862\/.f?formid=8&amp;h=AAFdikaIHLKEukB9P_KfjbDOtxOZxhR8sm3tff5M3xp4lunfeUM&amp;redirect_count=1&amp;did_javascript_redirect=T\" target=\"_blank\" rel=\"noopener\">get a quote<\/a>. ***<\/strong><\/span><\/p>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><span style=\"color: #ff8c00;\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p>Microvascular endothelial cells play a central role in inflammation, tumor metastasis, wound healing and tissue engineering [1]. They line the blood vessels and contribute to many biological processes such as hematosis, coagulation and trafficking of lymphocytes. The endothelial cell is of primary importance in the extravasation of leukocytes from the circulation into sites of tissue inflammation. The structure and function of endothelial cells are differentially regulated in space and time. In the case of prostate cancer, the interactions between prostate cancer cells with endothelial cells in the microvessels play an important role in prostate tumor metastasis. Study results suggest that prostatic endothelial cells may be actively involved in prostate growth, due to the secretion of regulatory factors such as IL-6 [2]<\/p>\n<p>iXCells Biotechnologies provides high quality Human Prostate Microvascular Endothelial Cells (HPMEC), which are isolated from human prostate tissue and cryopreserved at P2, with &gt;0.5 million cells in each vial. HPMEC express vWF\/Factor VIII, CD31 (PECAM), and Dil-Ac-LDL by uptake. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in <a style=\"line-height: 20.8px;\" href=\"https:\/\/ixcellsbiotech.com\/product\/endothelial-cell-growth-medium\/\">Endothelial Cell Growth Medium (Cat# MD-0010)<\/a> under the condition suggested by iXCells Biotechnologies.<\/p>\n<p><strong style=\"color: #ff8c00; font-size: 14px; line-height: 22.4px;\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px; width: 724px;\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px;\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px;\">H<span style=\"line-height: 20.8px;\">uman prostatetissue<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Package Size<\/strong><\/td>\n<td style=\"width: 592px;\">0.5 millioncells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Passage Number<\/strong><\/td>\n<td style=\"width: 592px;\">P2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Shipped<\/strong><\/td>\n<td style=\"width: 592px;\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Storage<\/strong><\/td>\n<td style=\"width: 592px;\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Growth Properties<\/strong><\/td>\n<td style=\"width: 592px;\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\"><strong> Media<\/strong><\/td>\n<td style=\"width: 592px;\"><a style=\"line-height: 20.8px;\" href=\"https:\/\/ixcellsbiotech.com\/product\/endothelial-cell-growth-medium\/\">Endothelial Cell Growth Medium (Cat# MD-0010)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><strong><span style=\"color: #ff8c00;\">References<\/span><\/strong><\/span><\/p>\n<p>[1] Richard, L., Velasco, P. and Detmar, M. (1998) Isolation and culture of microvascular endothelial cells. Method in Molecular Medicine 18:261-269.<\/p>\n<p>[2] Stachon, A., Schl?ter, T., K?ller, M., Weisser, H. and Krieg, M. (2001) Primary culture of microvascular endothelila cells from human bening prostatic hyperplasia. Prostate 48(3):156-164.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Microvascular endothelial cells play a central role in inflammation, tumor metastasis, wound healing and tissue engineering [1]. They line the blood vessels and contribute to many biological processes such as hematosis, coagulation and trafficking of lymphocytes. The endothelial [&hellip;]<\/p>\n","protected":false},"featured_media":99785,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[],"cell_system":[],"organ":[],"disease":[],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73774","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","first","instock","taxable","shipping-taxable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Prostate Microvascular Endothelial Cells (HPMEC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-prostate-microvascular-endothelial-cells-hpmec\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Prostate Microvascular Endothelial Cells (HPMEC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"*** Product available by custom isolation only, please contact us to get a quote. *** Product Description Microvascular endothelial cells play a central role in inflammation, tumor metastasis, wound healing and tissue engineering [1]. 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