{"id":73722,"date":"2023-05-22T05:37:21","date_gmt":"2023-05-22T12:37:21","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-chondrocytes-rheumatoid-arthritis-hc-ra\/"},"modified":"2023-08-04T03:33:21","modified_gmt":"2023-08-04T10:33:21","slug":"human-chondrocytes-rheumatoid-arthritis-hc-ra","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-chondrocytes-rheumatoid-arthritis-hc-ra\/","title":{"rendered":"Human Chondrocytes &#8211; Rheumatoid Arthritis (HC-ra)"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-size: 14pt;\"><strong>*** Product available by custom isolation only, please contact us to <a href=\"https:\/\/5176862.extforms.netsuite.com\/app\/site\/crm\/externalleadpage.nl\/compid.5176862\/.f?formid=8&amp;h=AAFdikaIHLKEukB9P_KfjbDOtxOZxhR8sm3tff5M3xp4lunfeUM&amp;redirect_count=1&amp;did_javascript_redirect=T\">get a quote.<\/a> ***<\/strong><\/span><\/p>\n<p style=\"line-height: 20.7999992370605px;\"><span style=\"font-size: 14px;\"><span style=\"color: #ff8c00;\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p>HC-ra Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis. Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in <span style=\"line-height: 20.8px;\">rheumatoid arthritis<\/span> cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-ra can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-ra can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies.<\/p>\n<p>iXCells Biotechnologies provides high quality Human Chondrocytes-Rheumatoid Arthritis (HC-ra), which are isolated from human articular cartilage of donors with rheumatoid arthritis and cryopreserved at P1, with &gt;0.5 million cells in each vial. These HC-ra are positive for aggrecan after differentiation and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HC-ra can further expand for 10 population doublings in <a href=\"https:\/\/ixcellsbiotech.com\/product\/chondrocyte-medium\/\">Chondrocyte Medium (Cat# MD-0040)<\/a> under the condition suggested by iXCells Biotechnologies.<\/p>\n<p>&nbsp;<\/p>\n<p><strong style=\"color: #ff8c00; font-size: 14px; line-height: 22.4px;\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px; width: 724px;\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px;\">Tissue<\/td>\n<td style=\"width: 592px;\">H<span style=\"line-height: 20.8px;\">uman articular cartilage of donors with rheumatoid arthritis<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Package Size<\/td>\n<td style=\"width: 592px;\">0.5 millioncells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Passage Number<\/td>\n<td style=\"width: 592px;\">P1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Shipped<\/td>\n<td style=\"width: 592px;\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Storage<\/td>\n<td style=\"width: 592px;\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Growth Properties<\/td>\n<td style=\"width: 592px;\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px;\">Media<\/td>\n<td style=\"width: 592px;\"><a href=\"https:\/\/ixcellsbiotech.com\/product\/chondrocyte-medium\/\"><span style=\"line-height: 20.8px;\">Chondrocyte Medium<\/span><span style=\"line-height: 20.8px;\">(Cat# MD-0040)<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>*** Product available by custom isolation only, please contact us to get a quote. *** Product Description HC-ra Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis. Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual [&hellip;]<\/p>\n","protected":false},"featured_media":99407,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[],"cell_system":[],"organ":[],"disease":[],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73722","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","first","instock","taxable","shipping-taxable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Chondrocytes - Rheumatoid Arthritis (HC-ra) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-chondrocytes-rheumatoid-arthritis-hc-ra\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Chondrocytes - Rheumatoid Arthritis (HC-ra) - iXCells\" \/>\n<meta property=\"og:description\" content=\"*** Product available by custom isolation only, please contact us to get a quote. *** Product Description HC-ra Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis. 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