{"id":73662,"date":"2023-05-22T05:33:21","date_gmt":"2023-05-22T12:33:21","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-pulmonary-artery-endothelial-cells-hpaec\/"},"modified":"2026-06-17T14:52:35","modified_gmt":"2026-06-17T21:52:35","slug":"human-pulmonary-artery-endothelial-cells-hpaec","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-pulmonary-artery-endothelial-cells-hpaec\/","title":{"rendered":"Human Pulmonary Artery Endothelial Cells (HPAEC)"},"content":{"rendered":"<p style=\"line-height: 20.7999992370605px\"><span style=\"color: #ff8c00\"><strong>Product Description<\/strong><\/span><\/p>\n<p>The pulmonary vasculature is of great physiological\/pathological significance. Human Pulmonary Artery Endothelial Cells (HPAEC) <span style=\"line-height: 1.6\">are critical to maintain the function of the pulmonary circulation and effective diffusion capacity of the lung. HPAEC provide a useful tool for studying various aspects of pathology and biology of the lung vasculature <\/span><em style=\"line-height: 1.6\">in vitro<\/em><sup> [1]<\/sup><span style=\"line-height: 1.6\">.<\/span><\/p>\n<p>iXCells Biotechnologies provides high quality HPAEC, which are isolated from human pulmonary artery from single donors and cryopreserved at P2, with &gt;0.5 million cells in each vial. HPAEC express vWF\/Factor VIII and CD31 (Figure 1) and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand in Endothelial Cell Growth Media under the condition suggested by iXCells Biotechnologies.<\/p>\n<p style=\"text-align: center\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/HPAECs.jpg\" alt=\"HPAECs\" width=\"600\" height=\"469\" \/><\/p>\n<p style=\"line-height: 20.8px;text-align: center\"><strong>Figure 1.<\/strong> HPAEC provided by iXCells are positive for CD31 <strong>(A)<\/strong> and vWF<strong> (B)<\/strong>, as shown by immunostaining. F<span style=\"line-height: 20.8px;text-align: center\">low analysis showed that m<\/span>ore than 99% of cells are CD31 positive<strong> (A&#8217;)<\/strong> and more than 97% are vWF positive<strong> (B&#8217;)<\/strong>.<\/p>\n<p style=\"line-height: 20.7999992370605px\"><strong style=\"color: #ff8c00;line-height: 22.3999996185303px\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">Human pulmonary artery<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5 million cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px\">Endothelial Cell Growth Media<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px\"><strong><span style=\"color: #ff8c00\">References<\/span><\/strong><\/p>\n<p>[1] Meuchel LW, Thompson MA, Cassivi SD, Pabelick CM and Prakash YS. Neurotrophins induce nitric oxide generation in human pulmonary artery endothelial cells. Cardiovasc Res. 2011; 91(4): 668-676.<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human Pulmonary Endothelial Cells.pdf\">Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description The pulmonary vasculature is of great physiological\/pathological significance. Human Pulmonary Artery Endothelial Cells (HPAEC) are critical to maintain the function of the pulmonary circulation and effective diffusion capacity of the lung. HPAEC provide a useful tool for studying various aspects of pathology and biology of the lung vasculature in vitro [1]. iXCells Biotechnologies [&hellip;]<\/p>\n","protected":false},"featured_media":90238,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2415],"cell_system":[2424,2427],"organ":[2440],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73662","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-endothelial-cells","cell_system-cardiovascular-system","cell_system-respiratory-system","organ-lung","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Pulmonary Artery Endothelial Cells (HPAEC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-pulmonary-artery-endothelial-cells-hpaec\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Pulmonary Artery Endothelial Cells (HPAEC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description The pulmonary vasculature is of great physiological\/pathological significance. 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