{"id":73660,"date":"2023-05-22T05:33:21","date_gmt":"2023-05-22T12:33:21","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-coronary-artery-endothelial-cells-hcaecs\/"},"modified":"2026-06-17T14:51:20","modified_gmt":"2026-06-17T21:51:20","slug":"human-coronary-artery-endothelial-cells-hcaecs","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-coronary-artery-endothelial-cells-hcaecs\/","title":{"rendered":"Human Coronary Artery Endothelial Cells (HCAECs)"},"content":{"rendered":"<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><span style=\"color: #ff7300\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<p style=\"text-align: justify\">Human Coronary Artery Endothelial Cells (HCAECs) line the vessel wall of coronary artery. They are extremely important in regulation of coronary blood flow and cardiac function. HCAEC has been used as a valuable <em>in vitro<\/em> model system to study the cardiovascular diseases such as thrombosis, atherosclerosis, hypertension, coronary artery diseases <sup>[1]<\/sup> and diabetes-related cardiovascular diseases <sup>[2]<\/sup>.<\/p>\n<p style=\"text-align: justify\"><strong>iXCells Biotechnologies<\/strong> provides high quality HCAECs, which are isolated from human coronary artery from single donors and cryopreserved at P2, with \u2265 0.5 million cells in each vial. These HCAECs express vWF\/Factor VIII, VE-Cadherin, and CD31. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand no more than 3 passages in Endothelial Cell Growth Media under the condition suggested by iXCells Biotechnologies.<\/p>\n<p style=\"text-align: justify\"><img fetchpriority=\"high\" decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/07\/Human_Coronary_Artery_Endothelial_Cells.webp\" alt=\"Human Coronary Artery Endothelial Cells\" width=\"1024\" height=\"252\" \/><strong> Figure 1. (A) <\/strong>HCAEC Phase contract <strong>(B)<\/strong> HCAEC CD31 staining <strong>(C)<\/strong>HCAEC vWF staining<\/p>\n<p>&nbsp;<\/p>\n<p style=\"line-height: 20.7999992370605px\"><strong style=\"color: #ff7300;font-size: 16px;line-height: 22.3999996185303px\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.8px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">Human coronary artery<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5 millioncells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px\">Endothelial Cell Growth Media<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><strong><span style=\"color: #ff7300\">References<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify\">[1] Besler C,et al and Landmesser U. Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. J Clin Invest. 2011; 121 (7): 2693-2708.<\/p>\n<p style=\"text-align: justify\">[2] Eriksson L and Nystrom T. Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosis. Cardiovasc Diabetol. 2014; 13:152<\/p>\n<p>&nbsp;<\/p>\n<p data-wp-editing=\"1\"><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/IXCells_Human_Coronary_Artery_Endothelial_Cells-V2.pdf\" target=\"_blank\" rel=\"noopener\">Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Human Coronary Artery Endothelial Cells (HCAECs) line the vessel wall of coronary artery. They are extremely important in regulation of coronary blood flow and cardiac function. HCAEC has been used as a valuable in vitro model system to study the cardiovascular diseases such as thrombosis, atherosclerosis, hypertension, coronary artery diseases [1] and diabetes-related [&hellip;]<\/p>\n","protected":false},"featured_media":90237,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2415],"cell_system":[2424],"organ":[2436],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73660","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-endothelial-cells","cell_system-cardiovascular-system","organ-aorta-blood-vessel","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Coronary Artery Endothelial Cells (HCAECs) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-coronary-artery-endothelial-cells-hcaecs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Coronary Artery Endothelial Cells (HCAECs) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Human Coronary Artery Endothelial Cells (HCAECs) line the vessel wall of coronary artery. 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