{"id":73591,"date":"2023-05-22T05:33:09","date_gmt":"2023-05-22T12:33:09","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-brain-vascular-pericytes-hbvp\/"},"modified":"2026-06-17T14:55:19","modified_gmt":"2026-06-17T21:55:19","slug":"human-brain-vascular-pericytes-hbvp","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-brain-vascular-pericytes-hbvp\/","title":{"rendered":"Human Brain Vascular Pericytes (HBVP)"},"content":{"rendered":"

Product Description<\/strong><\/p>\n

Pericytes are contractile cells that wrap around the endothelial cells of capillary and venules throughout the body [1]<\/sup>. Pericytes are embedded in basement membrane, where they communicate with endothelial cells by means of direct physical contact and paracrine signaling [2]<\/sup>. In the brain, pericytes help sustain the blood-brain barriers, which regulate capillary blood flow, the clearance and phagocytosis of cellular debris and the permeability of the blood-brain barrier. Pericytes deficiency in the central nervous system can cause the blood-brain barrier breakdown, leading to neurodegenerative diseases.<\/p>\n

iXCells Biotechnologies<\/strong> provides high quality Human Brain Vascular Pericytes (HBVP), which are isolated from human brain and cryopreserved at P2, with >0.5 million cells in each vial. These HBVP are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand for no more than 3 passages in Human\u00a0Pericyte Growth Medium (Cat# MD-0030)<\/a>\u00a0under the condition suggested by iXCells Biotechnologies. Additional expansion is not recommended, because the purity of pericyte population may decrease.<\/p>\n

\"Human<\/p>\n

Figure 1. <\/strong>Human Brain Vascular Pericytes (HBVP). (A) <\/strong>Phase contrast image of HBVP. (B)<\/strong> Immunofluorescence staining with antibody against Anti-alpha smooth muscle Actin (\u03b1-SMA).<\/p>\n

 <\/p>\n

Product Details<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n
Tissue<\/span><\/td>\nHuman Brain Vascular Pericytes (HBVP)<\/span><\/td>\n<\/tr>\n
Package Size<\/span><\/td>\n0.5 x 106<\/sup> cells\/vial<\/td>\n<\/tr>\n
Passage Number<\/span><\/td>\nP2<\/span><\/td>\n<\/tr>\n
Shipped<\/span><\/td>\nCryopreserved<\/span><\/td>\n<\/tr>\n
Storage<\/span><\/td>\nLiquid nitrogen<\/span><\/td>\n<\/tr>\n
Growth Properties<\/span><\/td>\nAdherent<\/span><\/td>\n<\/tr>\n
Media<\/span><\/td>\nPericyte Growth Medium (Cat# MD-0030)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

References<\/strong><\/p>\n

[1] \u00a0Birbrair etc and Osvaldo. Role fo pericytes in skeletal muscle regeneration and fat accumulation. Stem Cell and Development 2013, 22(16): 2298-2314.<\/p>\n

[2] \u00a0Bergers G and Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro-Oncology 2005, 7(4): 452-464.<\/p>\n

\u00a0Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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