{"id":73586,"date":"2023-05-22T05:33:08","date_gmt":"2023-05-22T12:33:08","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-peripheral-blood-cd8-cytotoxic-t-cells-positive-selection\/"},"modified":"2026-06-16T15:06:03","modified_gmt":"2026-06-16T22:06:03","slug":"human-peripheral-blood-cd8-cytotoxic-t-cells-positive-selection","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-peripheral-blood-cd8-cytotoxic-t-cells-positive-selection\/","title":{"rendered":"Human Peripheral Blood CD8+ Cytotoxic T Cells (Positive Selection)"},"content":{"rendered":"<p><strong style=\"color: #ff8c00\">Product Description<\/strong><\/p>\n<p>The CD8+ T cells, also known as Cytotoxic T cells (T<sub>C<\/sub> cells), are a type of T cells that kill cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways. Most cytotoxic T cells express T-cell receptors (TCRs) that can recognize a specific antigen, and a glycoprotein called CD8 which binds to the constant portion of the class I MHC molecule. When exposed to infected\/dysfunctional somatic cells, CD8+ T cells release the cytotoxins perforin, granzymes, and granulysin, which triggers the caspase cascade and eventually leads to apoptosis. CD8+ T cells have been implicated in the pathogenesis of hepatitis B virus infection <sup>[<\/sup><sup>1]<\/sup>, arthritis <sup>[2]<\/sup> etc.<\/p>\n<p><strong>iXCells Biotechnologies<\/strong> offers CD8+ T cells isolated from normal human peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic selection. &gt; 90% of the cells are CD8+ as showed by flow cytometric analysis (Figure 1).<\/p>\n<p style=\"text-align: center\"><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells.jpg\"><img fetchpriority=\"high\" decoding=\"async\" data-attachment-id=\"106739\" data-permalink=\"https:\/\/ixcellsbiotech.com\/?attachment_id=106739\" data-orig-file=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells.jpg\" data-orig-size=\"1039,1013\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"10HU-024-Datasheet-image-iXCells\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-1024x998.jpg\" class=\"alignnone wp-image-106739 size-large\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-1024x998.jpg\" alt=\"\" width=\"800\" height=\"780\" srcset=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-1024x998.jpg 1024w, https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-300x292.jpg 300w, https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-768x749.jpg 768w, https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells-600x585.jpg 600w, https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/05\/10HU-024-Datasheet-image-iXCells.jpg 1039w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/a><\/p>\n<p style=\"text-align: center\"><b><span style=\"line-height: 115%;color: #404040;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial\">Figure 1<\/span><\/b><span style=\"line-height: 115%;color: #404040;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial\">. Flow cytometric analysis showed that &gt;90% of the cells are CD8+.<\/span><\/p>\n<p style=\"line-height: 20.8px\"><strong style=\"color: #ff8c00;line-height: 22.4px\">Product Details<\/strong><\/p>\n<table style=\"width: 724px\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>issue<\/strong><\/td>\n<td style=\"width: 591px\">Normal human peripheral blood<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 591px\">5.0&#215;10<sup>6<\/sup> cells\/vial, 1.0&#215;10<sup>7<\/sup> cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Purity<\/strong><\/td>\n<td style=\"width: 591px\">&gt;90%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 591px\">P0<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 591px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 591px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 591px\">Suspension<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 591px\"><a href=\"https:\/\/ixcellsbiotech.com\/product\/blood-cell-culture-medium\/\" target=\"_blank\" rel=\"noopener\">Blood Cell Culture Medium (Cat# MD-0007)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong><span style=\"color: #ff8c00\">References<\/span><\/strong><\/p>\n<p>[1] Iannacone, Matteo; Sitia, Giovanni; Guidotti, Luca G (2006). &#8220;Pathogenetic and antiviral immune responses against hepatitis B virus&#8221;. <em>Future Virology<\/em> <strong>1<\/strong> (2): 189\u201396.<\/p>\n<p>[2] Subramanian S and Ramalingam K (2005). &#8220;Electron microscopic evidence on the participation Cytotoxic T Lymphocytes and Macrophages in Mtb adjuvant induced connective tissue inflammation and arthritogenesis in Rattus norvegicus&#8221;. <em>Asian Journal of Microbiology, Biotechnology and Environmental Sciences<\/em> <strong>7<\/strong> (2): 227\u2013233.<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/07\/10HU-024_Human-Peripheral-Blood-CD8-Cytotoxic-T-Cells-Positive-Selection.pdf\">Download Datasheet<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description The CD8+ T cells, also known as Cytotoxic T cells (TC cells), are a type of T cells that kill cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways. Most cytotoxic T cells express T-cell receptors (TCRs) that can recognize a specific antigen, and a [&hellip;]<\/p>\n","protected":false},"featured_media":90227,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[2245,2252],"cell_type":[2419],"cell_system":[2425],"organ":[2449],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73586","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","product_tag-cd8","product_tag-cd8-cytotoxic-t-cells-positive-selection","cell_type-immune-cells","cell_system-immune-and-hematopoietic-system","organ-blood-peripheral-blood-immune-system","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Peripheral Blood CD8+ Cytotoxic T Cells (Positive Selection) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-peripheral-blood-cd8-cytotoxic-t-cells-positive-selection\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Peripheral Blood CD8+ Cytotoxic T Cells (Positive Selection) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description The CD8+ T cells, also known as Cytotoxic T cells (TC cells), are a type of T cells that kill cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways. 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