{"id":73584,"date":"2023-05-22T05:33:08","date_gmt":"2023-05-22T12:33:08","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-vein-endothelial-cells-huvec\/"},"modified":"2026-07-31T13:09:14","modified_gmt":"2026-07-31T20:09:14","slug":"human-umbilical-vein-endothelial-cells-huvec","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-vein-endothelial-cells-huvec\/","title":{"rendered":"Human Umbilical Vein Endothelial Cells (HUVEC)"},"content":{"rendered":"<p style=\"line-height: 20.7999992370605px\"><span style=\"font-size: 16px\"><span style=\"color: #ff8c00\"><strong>Product Description<\/strong><\/span><\/span><\/p>\n<div>\n<p style=\"text-align: justify\">Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical cord. They are used as a laboratory model system for the study of the function and pathology of endothelial cells (e.g., angiogenesis) <sup>[1]<\/sup>. They are used due to their low cost, and simple techniques for isolating them from umbilical cords, which are normally resected after childbirth <sup>[2]<\/sup>. HUVECs can be easily made to proliferate in a laboratory setting. They exhibit a cobblestone phenotype when lining vessel walls.<\/p>\n<p style=\"text-align: justify\"><strong>iXCells Biotechnologies<\/strong> provides high quality Human Umbilical Vein Endothelial Cells (HUVEC), which are isolated from human umbilical vein of mix donors, and cryopreserved at P2, with &gt;0.5 million cells in each vial. HUVEC have \u201ccobblestone\u201d morphology and positive staining with vWF\/Factor VIII and CD31. HUVEC are one of the mostly used cell types to study endothelial function in vitro, including angiogenesis<sup> [1]<\/sup>, signaling pathway under normal and pathological condition such as oxidative stress, hypoxia<sup> [2]<\/sup> and inflammation etc. These HUVEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi and can further expand no more than 3 passages in Endothelial Cell Growth Media\u00a0under the condition suggested by iXCells Biotechnologies. Additional expansion may decrease the purity.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><img decoding=\"async\" style=\"display: block;margin-left: auto;margin-right: auto\" src=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human_Umbilical_Vein_Endothelial_Cells.png\" alt=\"Human Umbilical Vein Endothelial Cells\" \/><\/p>\n<\/div>\n<p style=\"text-align: center\"><strong>Figure 1. <\/strong>Human Umbilical Vein Endothelial Cells (HUVEC). (<strong>A<\/strong>) Phase contrast image of HUVEC. (<strong>B &amp; C<\/strong>) Immunofluorescence staining with antibodies against vWF (B) and CD31 (C).<\/p>\n<p>&nbsp;<\/p>\n<p style=\"line-height: 20.7999992370605px\"><strong style=\"color: #ff7300;font-size: 16px;line-height: 22.3999996185303px\">Product Details<\/strong><\/p>\n<table style=\"line-height: 20.7999992370605px;width: 724px\" border=\"1\" cellspacing=\"1\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 132px\"><strong>Tissue<\/strong><\/td>\n<td style=\"width: 592px\">Human umbilical cord tissue<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Package Size<\/strong><\/td>\n<td style=\"width: 592px\">0.5&#215;10<sup>6<\/sup>cells\/vial<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Passage Number<\/strong><\/td>\n<td style=\"width: 592px\">P2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Shipped<\/strong><\/td>\n<td style=\"width: 592px\">Cryopreserved<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Storage<\/strong><\/td>\n<td style=\"width: 592px\">Liquid nitrogen<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 135px\"><strong>Growth Properties<\/strong><\/td>\n<td style=\"width: 592px\">Adherent<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 132px\"><strong>Media<\/strong><\/td>\n<td style=\"width: 592px\">Endothelial Cell Growth Media<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"line-height: 20.7999992370605px\"><span style=\"color: #ff7300\"><span style=\"font-size: 16px\"><strong>References<\/strong><\/span><\/span><\/p>\n<p>[1] Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). &#8220;Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis&#8221;. <em>Stem Cell Rev<\/em> 2 (2): 93\u2013102.<\/p>\n<p>[2] Nallamshetty S, Chan SY, and Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013; 64: 20-30.<\/p>\n<p><a href=\"https:\/\/ixcellsbiotech.com\/wp-content\/uploads\/2023\/06\/Human_Umbilical_Vein_Endothelial_Cells_HUVEC_V2.pdf\" target=\"_blank\" rel=\"noopener\">Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Product Description Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical cord. They are used as a laboratory model system for the study of the function and pathology of endothelial cells (e.g., angiogenesis) [1]. They are used due to their low cost, and simple techniques for isolating [&hellip;]<\/p>\n","protected":false},"featured_media":90202,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2415],"cell_system":[2424],"organ":[2437],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73584","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-endothelial-cells","cell_system-cardiovascular-system","organ-umbilical-cord-placenta","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Umbilical Vein Endothelial Cells (HUVEC) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-umbilical-vein-endothelial-cells-huvec\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Umbilical Vein Endothelial Cells (HUVEC) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical cord. 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