{"id":73554,"date":"2023-05-22T05:33:03","date_gmt":"2023-05-22T12:33:03","guid":{"rendered":"https:\/\/ixcellsbiotech.com\/product\/human-dermal-fibroblasts-adult-hdf-a\/"},"modified":"2026-06-16T14:59:33","modified_gmt":"2026-06-16T21:59:33","slug":"human-dermal-fibroblasts-adult-hdf-a","status":"publish","type":"product","link":"https:\/\/ixcellsbiotech.com\/product\/human-dermal-fibroblasts-adult-hdf-a\/","title":{"rendered":"Human Dermal Fibroblasts-adult (HDF-a)"},"content":{"rendered":"

Product Description<\/span><\/span><\/strong><\/p>\n

Human Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing [1]<\/sup>. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The dermal fibroblast also has the unique title of being the first human somatic cell to be induced into a pluripotent stem cell line [2,3]<\/sup>.<\/p>\n

iXCells Biotechnologies<\/strong> provides high quality Human Dermal Fibroblasts (HDF) from normal donors including neonatal foreskin (Cat# 10HU-013<\/a>) and adult skin, or from adult skin of Type 1 Diabetes (Cat# 10HU-219<\/a>) patients. These cells are derived from the dermis of normal human neonatal foreskin or adult skin and cryopreserved at the end of primary culture. HDF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand inFibroblast Growth Medium (Cat# MD-0011<\/a>) for no more than 3 passages under the condition suggested by iXCells Biologies. Further expansion may decrease the proliferation rate and purity.<\/p>\n

 <\/p>\n

\"Human<\/p>\n

Figure 1. (A) <\/span><\/b>Human Neonatal Dermal Fibroblasts (10HU-013). (B)<\/b> Human Adult Dermal Fibroblasts (10HU-014).<\/span><\/p>\n

 <\/p>\n

Product Details<\/strong><\/p>\n\n\n\n\n\n\n\n\n
Tissue<\/strong><\/td>\nHuman Dermal Fibroblasts, Normal (Neonatal foreskin, adult skin)<\/td>\n<\/tr>\n
Package Size<\/strong><\/td>\n0.5×106<\/sup>cells\/vial, 1.0×106<\/sup>cells\/vial<\/td>\n<\/tr>\n
Shipped<\/strong><\/td>\nCryopreserved<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\nLiquid nitrogen<\/td>\n<\/tr>\n
Growth Properties<\/strong><\/td>\nAdherent<\/td>\n<\/tr>\n
Media<\/strong><\/td>\nFibroblast Growth Medium (Cat# MD-0011)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

References<\/strong><\/p>\n

[1] Lauren E. Tracy, Raquel A. Minasian, and E.J. Caterson (2016) Extracellular Matrix and Dermal Fibroblast Function in the Healing Wound. Adv Wound Care (New Rochelle). 2016 Mar 1; 5(3): 119\u2013136.<\/p>\n

[2] Takahashi K, Yamanaka S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell; 126:663\u2013676.<\/p>\n

[3] Kazutoshi Takahashi 1, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell; 131:861\u2013872.<\/p>\n

 <\/p>\n

Download Datasheet<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Product Description Human Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing [1]. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The […]<\/p>\n","protected":false},"featured_media":90203,"template":"","meta":{"_acf_changed":false,"content-type":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"product_brand":[],"product_cat":[1644],"product_tag":[],"cell_type":[2417],"cell_system":[2431],"organ":[2445],"disease":[2454],"research_area":[],"mutation":[],"mutation_type":[],"disease_model":[],"parental_line_name":[],"class_list":["post-73554","product","type-product","status-publish","has-post-thumbnail","product_cat-human-primary-cells","cell_type-fibroblasts","cell_system-integumentary-system-skin-and-connective-tissue","organ-skin","disease-normal-healthy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"exclude_global_add_ons":[],"addons":[],"acf":[],"yoast_head":"\nHuman Dermal Fibroblasts-adult (HDF-a) - iXCells<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ixcellsbiotech.com\/product\/human-dermal-fibroblasts-adult-hdf-a\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Dermal Fibroblasts-adult (HDF-a) - iXCells\" \/>\n<meta property=\"og:description\" content=\"Product Description Human Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing [1]. 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